TīmeklisZINPLAVA concentrated injection is a sterile, preservativefree, clear to moderately opalescent, - colourless to pale yellow liquid that requires dilution for intravenous infusion. Each vial contains bezlotoxumab and the following inactive ingredients: sodium chloride, sodium citrate dihydrate, TīmeklisZinplava Swiss Risk Management Plan Summary V2.2 Proprietary Swiss Summary of the Risk Management Plan (RMP) for Zinplava® (Bezlotoxumab 1000mg) …
Bezlotoxumab - Wikipedia
TīmeklisZINPLAVA is a human monoclonal antibody that binds to Clostridium difficile toxin B indicated to reduce recurrence of Clostridium difficile infection (CDI) in patients 18 years of age or older who are receiving … Tīmeklis2016. gada 4. dec. · The biggest thing to watch out for with Zinplava is worsening heart failure. But the risk seems to mostly pertain to patients with existing heart failure. In patients with a history of heart failure, 12.7% patients (15/118) in the Zinplava group versus 4.8% (5/104) in the placebo group experienced the major adverse event of … grant boyhood home georgetown ohio
Coverage Information for ZINPLAVA™ (bezlotoxumab) Official Site
Tīmeklisa CLcr estimated by the Cockcroft-Gault formula. (2.3) b Calculate dosage using Total Body Weight (TBW). For patients with TBW greater than IBW by 25% or more, use adjusted body weight. (2.3) • See Full Prescribing Information for subsequent dosage TīmeklisZINPLAVA-treated patients and 33% of placebo-treated patients. Heart failure was reported as a serious adverse reaction in 2.3% of the ZINPLAVA-treated patients and 1.0% of the placebo-treated patients [see Warnings and Precautions (5.1)]. One patient discontinued the ZINPLAVA infusion due to ventricular tachyarrhythmia that … TīmeklisZINPLAVA is a human monoclonal antibody that binds to Clostridium difficile toxin B indicated to reduce recurrence of Clostridium difficile infection (CDI) in patients 18 years of age or older who are receiving antibacterial drug treatment of CDI and are at high risk for CDI recurrence.. ZINPLAVA is not indicated for the treatment of CDI. ZINPLAVA … grant boyette pearl ms