WitrynaCurrent data suggest that FKBP12 functions as a "guardian" for the type I receptors to prevent them from leaky signaling under sub-optimal ligand concentrations, thereby … Witrynaimmunophilin protein family, which are involved in immunor-egulation and basic cellular processes including chaperonin-mediated protein folding and intracellular trafficking. …

The FKBP-associated protein FAP48 is an antiproliferative ... - PNAS

WitrynaFK506-binding proteins (FKBP) belong to the immunophilin family and are best known for their ability to enable the immunosuppressive properties of FK506 and rapamycin. For rapamycin, this is achieved by inducing inhibitory ternary complexes with the kinase mTOR. The essential accessory protein for this gain-of-function was thought to be … Witryna1 gru 2024 · This study systematically analyzed members of the apple cyclophilin family and confirmed the involvement of MdCYP16 as a nuclear-localized MD CYP that acts … curl and wget

Nadia Romina Zgajnar - Postdoctoral Research Scientist - LinkedIn

WitrynaNicholas J Turner. Cyclophilin A (CypA) is a member of the immunophilin family of proteins and receptor for the immunosuppressant drug cyclosporin A (CsA). Here we describe the design and ... Witryna18 lut 2024 · FK506-binding protein like (FKBPL) is a divergent member of the immunophilin family known for its role as a secreted anti-angiogenic protein that exhibits its action via CD44, establishing its critical role in angiogenesis [9,10]. Additionally, FKBPL has been shown to regulate steroid receptor and inflammatory … WitrynaThe protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein … curl api key header