WebWFDC2. WAP four-disulfide core domain protein 2 - also known as Human Epididymis Protein 4 [5] (HE4) - is a protein that in humans is encoded by the WFDC2 gene. [6] [7] … WebHE4 had a significantly higher area under the curve than CA125 (0.99 vs 0.91), with a sensitivity and specificity of 98% and 100%, respectively.10 Mean HE4 levels were found to be significantly higher in patients with endometrial or ovarian cancer than in patients with ovarian endometriomas or other types of
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WebApr 30, 2024 · The HE4 assays will be performed using the electrochemiluminescence (ECL) technique on Cobas Pro module E801, Roche Diagnostics. The HE4 assay is based on a sandwich-type electrochemiluminescence method. The HE4 assay with the Roche Diagnostics Elecsys reagent has been standardized against the Fujirebo Diagnostics … WebObjective: To investigate the value of human epididymis secretory protein 4(HE4) combined with CA125 assay in differential diagnosis of endometriosis cyst and ovarian malignant tumor. Methods: The level of HE4 and CA125 were measured by enzyme-linked immunosorbent assay (ELISA) in the serum specimens of 46 cases in endometriosis cyst … romans for all have sinned and fall short
HE4 reference range in healthy populations according to …
WebHE4 compliments CA 125 as an ovarian cancer marker. The combination of CA 125 and HE4 has higher sensitivity than either marker alone particularly in premenopausal women. HE4, together with CA 125 and menopausal status, make up the Risk of Malignancy Algorithm (ROMA) use to assess risk of ovarian cancer in patients with a pelvic mass, … WebMay 15, 2024 · The determination of tumor markers in the blood is an essential component of the diagnosis, follow-up control and monitoring of malignant tumors. HE4 (Human epididymis protein 4) is a marker with valuable statements in the diagnosis of ovarian carcinoma. It is characterized by high sensitivity and specificity. But due to its low … WebNov 2, 2014 · HE4 has been demonstrated to yield a higher sensitivity and specificity than that of CA125 serum marker when differentiating epithelial ovarian cancer from benign … romans game