WebMay 10, 2001 · Tishkoff, S. A. et al. Global patterns of linkage disequilibrium at the CD4 locus and modern human origins. Science 271 , 1380–1387 (1996). Article ADS CAS Google Scholar WebMar 8, 1996 · PMID: 8596909. DOI: 10.1126/science.271.5254.1380. Abstract. Haplotypes consisting of alleles at a short tandem repeat polymorphism (STRP) and an Alu …
Insights into recombination from patterns of linkage …
WebDec 5, 2013 · The results concerning genome-wide LD indicated that Duroc had “old inbreeding”, and confirmed the mixture history of Landrace and Yorkshire, which is also implied by the higher level of persistence of phase between Land race and Yorkshire. BackgroundThe extent of linkage disequilibrium (LD) is of critical importance for … WebThe patterns of LD with 28 SNPs are shown in Figure 1. As seen at many other loci 37, 38, the patterns of LD at COMT varied among populations studied (Figure 1) (somewhat different patterns exist using D' as shown in Supplementary Figure S1). In most populations high levels of LD exist in both the 5' and the 3' regions, but not in the coding ... quick scope kar98k mw
FULL PAPER Divergent patterns of linkage disequilibrium and …
[PDF] Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins Semantic Scholar DOI: 10.1126/science.271.5254.1380 Corpus ID: 4266475 Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins S. Tishkoff, E. Dietzsch, +12 authors K. Kidd Published 8 March 1996 Biology Science WebIn this review, we describe recent empirical and theoretical work on the extent of linkage disequilibrium (LD) in the human genome, comparing the predictions of simple population-genetic models to available data. Several studies report significant LD over distances longer than those predicted by standard models, whereas some data from short, intergenic … WebLinkage Disequilibrium Coe cient Can similarly show that D Ab = D AB and D ab = D AB LD is a property of two loci, not their alleles. Thus, the magnitude of the coe cient is important, not the sign. The magnitude of D does not depend on the choice of alleles. The range of values the linkage disequilibrium coe cient can take on varies with ... shipwreck maldives