Ctgf migration
WebJul 12, 2014 · Connective tissue growth factor (CTGF)/CCN family member 2 (CCN2) is a CCN family member of matricellular signaling modulators. It has been shown that … WebApr 11, 2024 · During chronic hepatitis B virus (HBV) infection, hepatic fibrosis is a serious pathological condition caused by virus-induced liver damage. The activation of hepatic stellate cells (HSCs) is a central event in the occurrence and progression of liver fibrosis. Although accumulating evidence has shown that HBV directly stimulates HSC activation, …
Ctgf migration
Did you know?
WebThe CTGF-mediated increases in κB-luciferase activities were inhibited by RGD, PD98059, U0126 or FAK, and ERK2 mutant. Taken together, our results indicated that CTGF … WebIn the former study, we discovered that the expression of adiponectin was obviously decreased in keloid tissues compared with those in normal controls, furthermore, adiponectin inhibited CTGF-mediated KFs proliferation, migration and the over-accumulation of ECM. 13 But the correlation between adiponectin and inflammatory …
WebCTGF can regulate the activity of diverse growth factors or integrins. 19,20 CTGF was found to activate the cellular proliferation, migration, and fibrogenesis. 21 CTGF has also been proven to participate in certain types of cancers of drug-resistance. WebApr 13, 2024 · The identification of tissue-specific promoters for gene therapeutic constructs is one of the aims of complex tumor therapy. The genes encoding the fibroblast …
WebConnective tissue growth factor (CTGF), a cystine-knot protein of the CCN family, interacts with a variety of biological response modifiers and participates in several biological processes such as cell proliferation, migration, differentiation, and development of bone, cartilage, and angiogenesis. TGF-b upregulates CTGF expression in ... WebOct 26, 2024 · Connective tissue growth factor (CTGF), also known as CCN family protein 2 (CCN2), is composed of four domains, including insulin-like growth factor binding …
WebJul 18, 2024 · This analysis also revealed several other up-regulated genes such as A2m and Nfkbiz as members of Il-6, Cxcl1, Ctgf, and Tgfb2 interactome . Future experimental studies may validate the potential role up-regulation of Il-6, Cxcl1, Ctgf, and Tgfb2 may have in promoting cancer cell migration, invasion, and cancer-induced bone metabolism.
WebJun 6, 2012 · These tumors demonstrate several phenotypes potentially related to CTGF function namely: cell migration, absent tumor cell apoptosis, as well as, reactive and well vascularised myofibroblast rich stroma and fibrosis development locally and in distal organs. ... Key roles for connective tissue growth factor (CTGF/CCN2) are demonstrated in the ... shutter hand job descriptionWebConnective tissue growth factor (CTGF), also known as CCN2, is a member of the CCN protein family of secreted proteins with roles in diverse biological processes. CTGF … shutter hangers for plastic shuttersWebCTGF promotes the migration of mesenchymal stem cells. A, mixed cell plating assay. HCT116 cells were seeded in 12-well plates at a low confluence and infected with AdCTGF or AdGFP. 15 h after ... shutter hangers for wood shuttersshutterhand certificateWebJan 31, 2024 · Recent studies have identified cell-derived connective tissue growth factor (CTGF) as a novel therapeutic target for the treatment of multiple human diseases, including various types of cancers [6 ... the palais hepburnWebCTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein). CTGF has important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, skeletal development, … the palais moontaWebConnective tissue growth factor (CTGF) is a signaling molecule with several roles in tissue repair and regeneration including promoting cell adhesion, cell migration, cell proliferation and angiogenesis. ... Results of the in vitro scratch assay shows that the membranes containing CTGF promoted cell migration and supported fast in vitro wound ... shutter hardware clips