Cisplatin salt wasting
WebCisplatin is a well-known chemotherapeutic agent that can be associated with hyponatremia. Mechanisms of cisplatin-induced hyponatremia include renal salt wasting … WebFeb 1, 2016 · The marked urinary losses of sodium in combination with a negative sodium balance led to the diagnosis of cisplatin-induced renal salt wasting syndrome (RSWS). The subsequent clinical...
Cisplatin salt wasting
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WebDifferential diagnosis of hyponatremia induced by cisplatin-containing chemotherapy: syndrome of inappropriate secretion of antidiuretic hormone (SIADH) or renal salt … WebContact ASN. 1401 H St, NW, Ste 900, Washington, DC 20005. [email protected]. 202-640-4660
WebCisplatin is an intercalating agent that induces apoptosis of cancer cells, and it has been the most widely used drug in the first-line chemotherapy. However, the increase in cisplatin-resistant cancer cells has become a major obstacle in clinical management of cancers (Amable, 2016 ). Web42%–100% of patients depending on total cisplatin dose and length of exposure. Hypomagnesemia and renal magnesium wasting may persist for up to 6 years after initial dose (5). Renal salt wasting syndrome has been reported in up to 10% of patients, manifesting as hyponatremia and severe ortho-static hypotension in the setting of high …
WebSalt wasting Cisplatin Azacitidine Syndrome of inappropriate antidiuresis Cyclophosphamide Vincristine Nephrogenic diabetes insipidus Cisplatin Ifosfamide Magnesium wasting Cetuximab, panitumumab Cisplatin Crystal nephropathy Methotrexate Acute interstitial nephritis Anti-CTLA-4 antibody WebFeb 16, 2024 · Cisplatin Carboplatin 11% (carboplatin likely lower) SIADH, renal salt wasting (tubular damage) Cyclophosphamide Ifosfamide 9%–52% SIADH BCR-ABL tyrosine kinase inhibitors Imatinib 9%–13% SIADH BRAF and VEGF tyrosine kinase inhibitors Axitinib Sorafenib Brivanib Pazopanib Sunitinib 16%–39% SIADH EGFR …
WebCisplatin induces both inflammation and vascular injury, which further promotes kidney injury. In addition to AKI, cisplatin causes proximal tubulopathy, salt wasting, loss of urinary concentrating ability, and magnesium wasting. View chapter Purchase book T cells in kidney injury and regeneration Li Li, ...
WebSIADH, renal salt-wasting syndrome, and salt loss caused by vomiting and/or anorexia, should be diagnosed as accurately as possible in future studies. ... Alhosaini MN, Patel A. Cisplatin-induced renal salt wasting syndrome. South Med J. 2010;103(8):793–799. 5. Raftopoulos H. Diagnosis and management of hyponatremia in cancer patients. pop os shop 无响应WebWe diagnosed this clinical condition as renal salt-wasting syndrome (RSWS) on the basis of dehydration and high urinary sodium excretion at the onset. In the second course of chemotherapy, CDDP was replaced with carboplatin (CBDCA); consequently, hyponatremia was not observed. sharex alternative macWebJan 25, 2012 · Hyponatremia associated with syndrome of inappropriate secretion of antidiuretic hormone (SIADH) or renal salt-wasting syndrome (RSWS) after platinum-based chemotherapy is not uncommon. However, no reports of RSWS following taxane monotherapy have been previously published. sharex alternative redditWebMar 1, 2024 · Cisplatin may produce renal salt wasting causing symptomatic orthostatic hypotension and hyponatremia associated with abnormalities of the renin-aldosterone … sharex 1 must be one of all row col noneWebNov 1, 2003 · In 1988, Hutchison et al reported profound urinary sodium wasting in 7 of 70 patients treated with cisplatin over an 18- month period in 1 institution. 1 All the patients were men with carcinomas (including 1 patient with SCLC) and presented 2-4 months after starting cisplatin-based therapy with signs of vol- ume depletion, urinary salt wasting ... popos shortcutsWebRenal salt wasting syndrome has been described in 17 case reports since 1984. It is a rare side effect of cisplatin that manifests with polyuria, hypovolemia, and hyponatremia, … sharex always uplaods to youtube at 480WebCisplatin-Induced Renal Salt Wasting Requiring over 12 Liters of 3% Saline Replacement Case Rep Nephrol. 2024;2024:8137078. doi: 10.1155/2024/8137078. Epub 2024 May 10. Authors Phuong-Chi Pham 1 , Pavani Reddy 1 , Shaker Qaqish 1 , Ashvin Kamath 1 , Johana Rodriguez 2 , David Bolos 2 , Martina Zalom 2 , Phuong-Thu Pham 3 … pop os slow boot