Cisplatin dye
WebCisplatin is commonly used as a viability stain in mass cytometry studies, however, recent work by Mei et al. has demonstrated that cisplatin can also be used to label antibodies, … WebDec 8, 2024 · Graphical Abstract. Real-time cisplatin trafficking: A mitochondria-targeting fluorescent probe was engineered to detect the clinically-important platinum drug …
Cisplatin dye
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WebGroups I and II were fed a basal diet, while groups III and IV were fed diets containing 0.5% and 1% sorghum leaf sheath dye, respectively, for 20 days before cisplatin administration. Hepatotoxicity was induced by a single dose of cisplatin (7 mg/kg body weight, i.p.), and the experiment was terminated at 3 days after cisplatin injection. WebSep 16, 2024 · It is most common in patients treated with ifosfamide and high-dose cyclophosphamide in the setting of bone and soft tissue sarcoma and hematopoietic cell transplantation, or as a late toxicity of pelvic radiation therapy (RT) when the bladder is within the radiation treatment field.
WebNov 23, 2024 · Cisplatin mediated CSC enrichment is well established in various cancers, yet the underlying mechanism is largely unknown. Cisplatin also promotes transcriptional upregulation of PIK3CA, hence activating PI3K/AKT signaling in resistant cells. WebJan 4, 2024 · The incidence, risk factors, clinical presentation, prevention, and management of extravasation injury from vesicants or irritants are reviewed here, with a focus on chemotherapy extravasation injury. Venous irritation (chemical phlebitis) that occurs with drug administration into a vein that remains intact (eg, vinorelbine and epirubicin), and ...
WebStudied cisplatin (major chemotherapeutic) accumulation and trafficking in KB 3-1 parental and resistant cell lines Determined IC50 concentrations … WebJun 15, 2008 · Cisplatin is rarely used in routine treatment of breast cancer, but may be useful in combination therapy as several recent studies have demonstrated the efficacy of platinum combinations with taxanes and trastuzumab [ 2 ].
WebMar 16, 2024 · Cisplatin-based chemotherapy is dominated in several cancers; however, insufficient therapeutic outcomes and systemic toxicity hamper their clinical applications. Controlled release of cisplatin and reducing inactivation remains an urgent challenge to overcome. Herein, diselenide-bridged mesoporous …
WebApr 13, 2024 · Consequently, miR-196a released from exosomes can confer cisplatin resistance to cancer cells by novel binding targets, CDKN1B and ING5, demonstrating that miR-196a could be a potential predictor ... highway jobs londonWebOct 21, 2024 · 1-DPA 2 can target both the externalized phosphatidylserine (PS) and active caspase-3 (Casp-3), two essential biomarkers of apoptosis, producing enhanced 808 nm … small swing arm bagWebNov 9, 2024 · Cisplatin is the most important and classic first-line synchronous chemotherapeutic agent for the treatment of nasopharyngeal carcinoma; ... and therefore the vital dye 7-AAD, in conjunction with annexin V, was used to allow discrimination of early apoptotic cells. Cells were treated with CATR alone (1 µM), cisplatin (20 µM) alone, or ... small swimwear for girlsWebStandard colony formation assay was used to determine the cytotoxicity of cisplatin. Parachute dye coupling assay was used to measure GJ function, and western blot analysis was used to determine the expression levels of Cx32. small swimwear brands ukWebMay 11, 2024 · Cisplatin ( cis -diamminedichloroplatinumII) is one of the most effective and commonly used chemotherapy drugs to treat solid malignant tumors in children and adults, often in combination with... highway johnny cashWebApr 10, 2024 · Triple-negative breast cancer (TNBC) is one of the most aggressive forms of breast cancer and constitutes 10–20% of all breast cancer cases. Even though platinum-based drugs such as cisplatin and carboplatin are effective in TNBC patients, their toxicity and development of cancer drug resistance often hamper their clinical use. Hence, novel … small swing and slideWebNov 21, 2024 · Cisplatin chemotherapy has been a mainstay of cancer treatment since its FDA approval in 1978. As the population of cancer survivors continues to grow, so does the importance of addressing the... highway j troy mo