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WebMay 10, 2016 · Like normal stem cells, tumor-initiating cells (T-ICs) are regulated extrinsically within the tumor microenvironment. Because HCC develops primarily in the context of cirrhosis, in which there is an enrichment of activated fibroblasts, we hypothesized that cancer-associated fibroblasts (CAFs) would regulate liver T-ICs. WebRui Chen 1 , Shancheng Ren 1 ; Chinese Prostate Cancer Consortium; Ming Kwong Yiu 2 , Ng Chi Fai 3 , Wai Sam Cheng 4 , Lap Hong Ian 5 , Seiji Naito 6 , Tadashi Matsuda 7 , Elijah Kehinde 8 , Ali Kural 9 , Jason Yichun Chiu 10 , Rainy Umbas 11 , Qiang Wei 12 , Xiaolei Shi 1 , Liqun Zhou 13 , Jian Huang 14 , Yiran Huang 15 , Liping Xie 16 , Lulin ... rac168u472jctp
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